Lysosome+Period+2

                                               __Lysosomes__                         <span style="font-family: 'Comic Sans MS', cursive;"> <span style="font-size: 80%; font-family: Arial, Helvetica, sans-serif;">__By: Shelby, and Marissa__               <span style="display: block; font-size: 110%; color: black; font-family: Arial, Helvetica, sans-serif; background-color: white; text-align: left;">      <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;">             <span style="display: block; font-size: 110%; color: black; font-family: Arial, Helvetica, sans-serif; background-color: white; text-align: left;">      <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;">              <span style="display: block; font-size: 110%; color: black; font-family: Arial, Helvetica, sans-serif; background-color: white; text-align: left;">      <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;">   **__ http://images.google.com/imgres?imgurl=http://www.maroteaux-lamy.com/English/images/HCP/MPSPhoLysosomes.jpg&imgrefurl= __**           <span style="display: block; font-size: 110%; color: black; font-family: Arial, Helvetica, sans-serif; background-color: white; text-align: left;">      <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;">   **__ http://www.maroteaux-lamy.com/English/HCP/BiochemBasis.aspx&usg=__j8ip_h3rMHFhmYtczxgdITHQ-qE=&h=224&w=342&sz=45&hl=en&start=32&um=1&tbnid=FvFGadJbGsGZAM:&tbnh=79&tbnw=120&prev=/images%3Fq%3Dlysosomes%26start%3D20%26ndsp%3D20%26um%3D1%26hl%3Den%26safe%3Doff%26rlz%3D1T4ADBF_enUS276US278%26sa%3DN __**           <span style="display: block; font-size: 110%; color: black; font-family: Arial, Helvetica, sans-serif; background-color: white; text-align: left;">      <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;">               <span style="display: block; font-size: 110%; color: black; font-family: Arial, Helvetica, sans-serif; background-color: white; text-align: left;">      <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;">     **__Functions:__** lysosomes are organelles that contain digestive enzymes that break down protiens, and neucleic acid. Its the digestive system of the cell. They also degrade worn out organelles such as the mitochondria. So any cell that is unwanted is broken down. Another function for lysosomes is to handle the products of receptor-mediated endocytosis such as the receptor, ligand and associated membrane. <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;"> **__Disorders:__** Inherited defects or deficiencies of lysosomal enzymes can result in accumulation of undegraded metabolites. There are alot of specific deficiencies. Storage diseases are usually grouped biochemically by the accumulated metabolite. some Subgroups are mucopolysaccharidoses, and sphingolipidoses.

__Sphingolipidoses:__ Sphingolipids are normal lipid components of cell membranes that accumulate in lysosomes and cause alot of neuronal, bone, and other changes when enzyme deficiencies prevent their breakdown. Gaucher's disease is the most common sphingolipidosis. <span style="display: block; font-size: 110%; color: black; font-family: Arial, Helvetica, sans-serif; background-color: white; text-align: left;">     <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;"> <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;"> **__Description:__** Its spherical with a single membrane. The size is variable, but usually between 200-400mn. In the cell the Lysosome is usually near the Golgi.

<span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;"> **__Interesting Facts:__**              <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;">      <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;"> <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;"> > <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;"> <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;"> Sources: http://library.thinkquest.org/12413/structures.html http://cellbio.utmb.edu/cellbio/lysosome.htmhttp://images.google.com/imgres?imgurl=http://library.thinkquest.org/06aug/01942/plcells/thinkquest/lysosomes.jpg&imgrefurl=https://aboutscience.wikispaces.com/cc4&usg=__tn2dvBeUEJcOSgDPEEHEV4dNs7A=&h=288&w=432&sz=27&hl=en&start=8&um=1&tbnid=C_6YuLXOX9F4WM:&tbnh=84&tbnw=126&prev=/images%3Fq%3Dwhat%2Blysosomes%2Blook%2Blike%26um%3D1%26hl%3Den%26safe%3Dactive%26sa%3DN
 * Lysosomes are found in animal cells, but rarely found in plant cells.
 * <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;">             Lysosome comes from two greek words, one meaning destruction, and two meaning body.      <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;">       <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;">
 * Lysosomes got a nickname "suicide-bags" because of there autophagic cell deaths, which means self-destructs.       <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;">       <span style="font-size: 100px; font-family: Arial, Helvetica, sans-serif;">
 * The cell breaks down if lysosome explodes